Computergestützte Epidemiologie
Mathematische Modellierung
Simulation
DE | EN | FR

Originalarbeiten

In Vorbereitung, zur Publikation angenommen oder in Druck

  • R. Fretschner, A. Heininger, W.A. Krueger, B. Kottler, A. Doebele, H. Kuehne, M. Eichner, K. Unertl (submitted)
    Influence of patients' age on resource utilization and efficiency of therapy in a surgical intensive care unit.

  • T. W. Orlikowsky, M. Muenzenmaier, M. Depperschmid, M. Eichner, R. Goelz, C. F. Poets (submitted)
    High sensitive C-reactive protein (hsCRP) levels in healthy newborns and those with suspected or culture proven early onset bacterial infection.

          Abstract

Aufsätze im Jahr 2009

  • Eichner M, Schwehm M, Duerr HP, Witschi M, Koch D, Brockmann SO, Vidondo B (2009).
    Antiviral prophylaxis during pandemic influenza may increase drug resistance.
    BMC Infect Dis.
    9:4 (e-pub).

Aufsätze im Jahre 2008

  • Brockmann SO, Schwehm M, Duerr HP, Witschi M, Koch D, Vidondo B, Eichner M (2008).
    Modeling the effects of drug resistant influenza virus in a pandemic.
    Virol J5: 133 (e-pub).


  • Duerr HP, Hoffmann WH, Eichner M. (2008).
    Does resistance to filarial reinfections become leaky over time?
    Trens Parasitol 24: 350-4.


  • Duerr HP, Raddatz G, Eichner M. (2008).
    Diagnostic value of nodule palpation in onchocerciasis.
    Trans Roy Soc Trop Med Hyg 102: 148-54.


  • Judenhofer MS, Wehrl HF, Newport DF, Catana C, Siegel SB, Becker M, Thielscher A, Kneilling M, Lichy MP, Eichner M, Klingel K, Reischl G, Widmaier S, Röcken M, Nutt RE, Machulla HJ, Uludag K, Cherry SR, Claussen CD, Pichler BJ. (2008).
    Simultaneous PET-MRI: a new approach for functional and morphological imaging.
    Nature Medicine 14: 459-65.


  • Krumkamp R, Duerr HP, Reintjes R, Ahmad A, Kassen A, Eichner M (2008).
    Impact of public health interventions in controlling the spread of SARS: modelling of intervention scenarios.
    Int J Hyg Environ Health 212: 67-75.


  • Nishiura H, Brockmann SO, Eichner M (2008).
    Extracting key information from historical data to quantify the transmission dynamics of smallpox.
    Theor Bio Med Model 5: 20 (e-pub).


  • Tzaribachev N, Kuemmerle-Deschner J, Eichner M, Horneff G. (2008).
    Safety and efficacy of etanercept in children with juvenile idiopathic arthritis below the age of 4 years.
    Rheumatol Int 28: 1031-4.

Aufsätze im Jahre 2007

  • D. Brötz, M. Eichner, T. Gasser, M. Weller, J.P. Steinbach (2007)
    Radicular and non-radicular back pain in Parkinson's disease: a controlled study.
    Movement Disorders22: 853-6.


  • K. Dietz, G Raddatz, J. Wallis, N. Muller, I. Zerr, H. P. Duerr, H. Lefevre, E. Seifried, J. Lower (2007)
    Blood transfusion and spread of variant Creutzfeldt-Jakob disease.
    Emerging Infectious Diseases 13: 89-96.


  • H. P. Duerr, S. O. Brockmann, I. Piechotowski, M. Schwehm, M. Eichner (2007)
    Influenza pandemic intervention planning using InfluSim: Pharmaceutical and non-pharmaceutical interventions.
    BMC Infectious Diseases 7: 76 (e-pub).


  • H. P. Duerr, M. Schwehm, C. C. Leary, S. J. de Vlas, M. Eichner (2007)
    The impact of contact structure on infecious disease control: influenza and antiviral agents.
    Epidemiology and Infection (Epub ahead of print)


  • M. Eichner, M. Schwehm, H. P. Duerr, SO Brockmann (2007)
    The influenza pandemic preparedness planning tool InfluSim.
    BMC Infectious Diseases 7: 17 (e-pub).


  • H. M. Häfner, K. Bräuer, M. Eichner, I. Koch, H. Heinle, M. Rocken, A. Strolin (2007)
    Wavelet Analysis of skin perfusion in healthy volunteers.
    Microcirculation 14: 137-44.


  • Kneilling M, Hültner L, Pichler BJ, Mailhammer R, Morawietz L, Solomon S, Eichner M, Sabatino J, Biedermann T, Krenn V, Weber WA, Illges H, Haubner R, Röcken M. (2007)
    Targeted mast cell silencing protects against joint destruction and angiogenesis in experimental arthritis in mice.
    Arthritis and Rheumatism 56: 1806-16.


  • C. C. Leary, M. Schwehm, M. Eichner, H. P. Duerr (2007)
    Tuning degree distributions of scale-free networks.
    Physica A: Statistical Mechanics and its Applications 382: 731-8.


  • H. Nishiura, M. Eichner (2007)
    Infectiousness of smallpox relative to disease age: estimates based on transmission network and incubation period..
    Epidemiol Infect (Epub ahead of print)


  • H. Nishiura, M. Eichner (2007)
    Interpreting the epidemiology of postexposure vaccination against smallpox.
    International Journal of Hygiene and Environmental Health (Epub ahead of print)


  • H. Nishiura, M. Eichner (2007)
    Predicting residual immunity against smallpox.
    Journal of Infectious Diseases 195: 160-1.

Aufsätze im Jahre 2006

  • H.P. Duerr, C.C. Leary, M. Eichner (2006)
    High infection rates at low transmission potentials in West African onchocerciasis.
    International Journal of Parasitology 36: 15-7.


  • M. Eichner, M. Schwehm, S. Brockmann (2006)
    Dynamische Simulation einer Influenza-Pandemie - Planungshilfe für Entscheidungsträger.
    Public Health Forum 14 (51): 15-7.


  • C. Gille C, B. Spring, T.J. Tewes, J. Loffler, G.E. Dannecker, M. K. Hoffmann, M. Eichner, C.F. Poets, T.W. Orlikowsky (2006)
    Diminished response to interleukin-10 and reduced antibody-dependent cellular cytotoxicity of cord blood monocyte-derived macrophages.
    Pediatric Research 60: 152-7.


  • H. Nishiura, I. Arita, M. Schwehm, M. Eichner (2006)
    Epidemiologic assessment of the protective effects of smallpox vaccination.
    American Journal of Infectious Diseases 2: 9-17.


  • H. Nishiura, M. Eichner (2006)
    Estimation of the duration of vaccine-induced residual protection against severe and fatal smallpox based on secondary vaccination failure.
    Infection 34: 241-6.


  • H. Nishiura, K. Dietz, M. Eichner (2006)
    The earliest notes no the reproduction number in relation to herd immunity: Theophil Lotz and smallpox vaccination.
    Journal of Theoretical Biology 241: 964-7.


  • H. Nishiura, M. Schwehm, M. Eichner (2006)
    Still protected against smallpox? Estimation of the duration of vaccine-induced immunity against smallpox.
    Epidemiology 17: 576-81.


  • H. Nishiura, M. Schwehm, M. Kakehashi, M. Eichner (2006)
    Transmission potential of primary pneumonic plague: time inhomogeneous evaluation based on historical documents of the transmission network.
    Journal of Epidemiology & Community Health 60:640-5.


  • T. W. Orlikowsky, C. Trüg, F. Neunhoeffer, M. Deperschmidt, M. Eichner, C. F. Poets (2006)
    Lipopolysaccharide-binding protein in noninfected neonates and those with suspected early-onset bacterial infection.
    J Perinatol. 26:115-9.


  • Z. Zhou, C. P. Cornelius, M. Eichner, A. Bornemann (2006)
    Reinnervation-induced alterations in rat skeletal muscle.
    Neurobiology of Disease 23: 595-602.

Aufsätze im Jahre 2005

  • H.P. Duerr, K. Dietz, M. Eichner (2005)
    Determinants of the eradicability of filarial infections: a conceptual approach.
    Trends in Parasitology21:88-96.


  • H. M. Häfner, K. Bräuer, M. Eichner, A. Steins, M. Möhrle, A. Blum, M. Jünger (2005)
    Wavelet analysis of cutaneous blood flow in melanocytic skin lesions.
    Journal of Vascular Research 42: 38-46.


  • B. Nohé, R. Ries, A. Ploppa, C. Zanke, M. Eichner, K. Unertl, H.-J. Dieterich (2005)
    Effects of intraoperative blood salvage on leukocyte recruitment to the endothelium.
    Anesthesiology 102: 300-7.


  • T. W. Orlikowsky, G. E. Dannecker, B. Spring, M. Eichner, M. K. Hoffmann, C. F. Poets (2005)
    Effect of dexamethasone on B7 regulation and T cell activation in neonates and adults.
    Pediatr Res. 57: 656-61.

Aufsätze im Jahre 2004

  • K. Auranen, M. Eichner, T. Leino, A.K. Takala, P.H. Mäkelä, T. Takala (2004)
    Modelling transmission, immunity and disease of Haemophilus influenzae type b in a structured population
    Epidemiol. Infect.132: 947-57.


  • H.P. Duerr, K. Dietz, H. Schulz-Key, D.W. Büttner, M. Eichner (2004)
    The relationships between the burden of adult parasites, host age and the microfilarial density in human onchocerciasis.
    International Journal for Parasitology 34: 463-73.


  • H.P. Duerr, M. Eichner, D. Ammermann (2004)
    Modelling senescence in hypotrichous ciliates.
    Protist 155: 45-52.


  • M. Eichner, M. Schwehm (2004)
    Smallpox. A vulnerable specter.
    Epidemiology 15: 258-60.


  • T. W. Orlikowsky, F. Neunhoeffer, R. Goelz, M. Eichner, Ch. Henkel, M. Zwirner, C. F. Poets (2004)
    Evaluation of IL-8-concentrations in plasma and lysed EDTA-blood in healthy newborns and neonates with early onset bacterial infection.
    Pediatr. Res. 56: 804-9.


  • Y. Zhang, K. Auranen, M. Eichner (2004)
    The influence of competition and vaccination on the coexistence ot two pneumococcal serotypes.
    Epidemiology and Infection 132: 1073-81.

Aufsätze im Jahre 2003

  • H.P. Duerr, K. Dietz, M. Eichner (2003)
    On the interpretation of age-intensity profiles and dispersion patterns in parasitological surveys.
    Parasitology126: 87-101.


  • H.P. Duerr, K. Dietz, H. Schulz-Key, D.W. Büttner, M. Eichner (2003)
    Density-dependent parasite establishment suggests infection-associated immunosuppression as an important mechanism for parasite density regulation in onchocerciasis.
    Transactions of the Royal Society of Tropical Medicine and Hygiene 97: 242-50.


  • M. Eichner, K. Dietz (2003)
    The transmission potential of smallpox: estimates based on detailed data from an outbreak.
    American Journal of Epidemiology 158: 110-7.


  • M. Eichner (2003)
    Case isolation and contact tracing can prevent the spread of smallpox.
    American Journal of Epidemiology 158: 118-28.


  • M. Eichner (2003)
    Analysis of historical data suggests long-lasting protective effects of smallpox vaccination.
    American Journal of Epidemiology 158: 717-23.


  • H. M. Häfner, S. R. Thomma, M. Eichner, A. Steins, M, Jünger (2003)
    The influence of Emla® cream on cutaneous microcirculation.
    Clinical Hemorheology and Microcirculation 28: 121-8.


  • A. K. Kirch, H. P. Duerr, B. Boatin, W. S. Alley, W. H. Hoffmann, H. Schulz-Key, P. T. Soboslay (2003)
    Impact of parental onchocerciasis and intensity of transmission on development and persistence of Onchocerca volvulus infection in offspring: an 18 year follow-up study.
    Parasitology 127: 327-35.

Aufsätze im Jahre 2002

  • K. Dietz, M. Eichner (2002)
    The effect of heterogeneous interventions on the spread of infectious diseases.
    XXIst International Biometric Conference (Freiburg, Germany).
    Proceedings - Manuscripts of Invited Papers: 159-173.

    Manuskript (PDF, 238 kB)


  • M. Eichner, H. H. Diebner, C. Schubert, H. W. Kreth, K. Dietz (2002)
    Estimation of the time-dependent vaccine efficacy from a measles epidemic.
    Statistics in Medicine 21: 2355-2368.

    Manuskript (PDF, 359 kB)

  • H. M. Häfner, M. Eichner (2002)
    Klinische Überprüfung des Anpressdruckes unterschiedlicher Konfektionsgrößen des zirkulären Kompressionsvertigverbandes Tubulcus®.
    Phlebologie 5: 108-111.


  • B. Nohé, M. Burchard, C. Zanke, M. Eichner, V. Krump-Konvalinkova, C. J. Kirkpatrick, H.-J. Dieterich (2002)
    Endothelial accumulation of hydroxyethyl starch and functional consequences on leukocyte-endothelial interactions. European Surgical Research 34: 364-372.

Aufsätze im Jahre 2001

  • H. P. Duerr, K. Dietz, D. W. Buettner, H. Schulz-Key (2001)
    A stochastic model for the aggregation of Onchocerca volvulus in nodules.
    Parasitology123: 193-201.


  • M. Eichner, H. H. Diebner, L. Molineaux, W. E. Collins, G. M. Jeffery, K. Dietz (2001)
    Genesis, sequestration and survival of Plasmodium falciparum gametocytes. Parameter estimates from fitting a model to malariatherapy data.
    Transactions of the Royal Society of Tropical Medicine and Hygiene 95: 497-501.


  • H. M. Häfner, M. Eichner, M. Jünger (2001)
    Medizinische Kompressionstherapie.
    Zentralblatt für Chirurgie 126: 551-556.


  • L. Molineaux, H. H. Diebner, M. Eichner, W. E. Collins, G. M. Jeffery, K. Dietz (2001)
    Plasmodium falciparum parasitaemia described by a new mathematical model.
    Parasitology 122: 379-91.

Aufsätze im Jahre 2000

  • H. H. Diebner, M. Eichner, L. Molineaux, W. E. Collins, G. M. Jeffery, K. Dietz (2000)
    Modelling the transition of asexual blood stages of Plasmodium falciparum to gametocytes.
    Journal of Theoretical Biology202: 113-127.


  • H. P. Duerr, K. Dietz (2002)
    Stochastic models for aggregation processes
    Mathematical Biosciences 165: 135-45.


  • H. M. Häfner, M. Eichner, B. Vollert, D. Zuder, M. Jünger (2000)
    Ein neues optoelektronisches Meßinstrument zur Erfassung von Beinumfängen im Vergleich zur manuellen Maßbandmessung.
    Biomedizinische Technik (Berl.) 45: 131-134.

Aufsätze im Jahre 1999

  • K. Auranen, M. Eichner, H. Käyhty, A. K. Takala, E. Arjas (1999)
    A hierarchical Bayesian model to predict the duration of immunity to Haemophilus influenzae Type b.
    Biometrics55: 1306-1313.


  • B. Nohé, H.-J. Dieterich, M. Eichner, K. Unertl (1999)
    Certain batches of albumin solutions influence the expression of endothelial cell adhesion molecules.
    Intensive Care Medicine 25: 1381-1385.


  • T. T. Zittel, J. Glatzle, M. E. Kreis, M. Starlinger, M. Eichner, H. E. Raybould, H. D. Becker, E. C. Jehle (1999)
    C-fos protein expression in the nucleus of the solitary tract correlates with cholecystokinin dose injected and food intake in rats.
    Brain Research 846: 1-11.

Aufsätze in den Jahren 1990 bis 1994

  • M. Eichner, A. Renz, G. Wahl, P. Enyong (1991)
    Development of Onchocerca volvulus microfilariae injected into Simulium species from Cameroon.
    Medical and Veterinary Entomology 5: 293-297.


  • M. Eichner, A. Renz (1990)
    Differential length of Onchocerca volvulusinfective larvae from the Cameroon rain forest and savanna.
    Tropical Medicine and Parasitology 41: 29-32.

Buchbeiträge im Jahr 2003

  • M. Eichner, M. Kretzschmar (2003)
    Mathematische Modelle in der Infektionsepidemiologie
    In A. Krämer, R. Reintjes (Ed.): "Infektionsepidemiologie. Methoden, Surveillance, Mathematische Modelle, Global Public Health. Springer Verlag, Heidelberg

Buchbeiträge im Jahr 2001

  • M. Eichner (2001)
    Kontraintuitive Effekte bei der Bekämpfung von Infektionskrankheiten
    In H. H. Diebner (Ed.): "Studium generale zur Komplexität"
    , Genista Verlag, Tübingen

    Manuskript (PDF, 1,3 MB)

Buchbeiträge vor 2001

  • K. Dietz, M. Eichner (1992)
    Infektionskrankheiten und deren Beeinflussung durch Schutzimpfungen.
    In H. Spiess, G. Maass (Ed.): Neue Schutzimpfungen - Impfempfehlungen, Aufklärung, Widerstände., München, 215-244.

  • M. Eichner, K. P. Hadeler, K. Dietz (1996)
    Stochastic models for the eradication of poliomyelitis: minimum population size for polio virus persistence.
    In: Valerie Isham, Graham Medley (Ed.): "Models for Infectious Human Diseases. Cambridge University Press, 315-327.

  • M. Eichner, S. Zehnder, K. Dietz (1996)
    An age-structured model for measles vaccination.
    In: Valerie Isham, Graham Medley (Ed.): "Models for Infectious Human Diseases. Cambridge University Press, 38-56.